CBY1/PGEA1 antibody (C-Term)

Catalog No. ABIN653093

Product Details anti-CBY1/PGEA1 Antibody

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Binding Specificity: AA 98-126, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HRIHFB2025 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HRIHFB2025.

Clone: RB23191

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CBY1/PGEA1 antibody (ABIN653093)

Yamano, Uzawa, Saito, Nakashima, Kasamatsu, Koike, Kouzu, Shinozuka, Nakatani, Negoro, Fujita, Tanzawa: "Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 2, pp. 437-49, (2009) (PubMed).

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: HRIHFB2025 (CBY1 Products)

Synonyms: chibby antibody, cby antibody, arb1 antibody, pgea1 antibody, pigea14 antibody, pigea-14 antibody, hs508i15a antibody, C22orf2 antibody, CBY antibody, HS508I15A antibody, PGEA1 antibody, PIGEA-14 antibody, PIGEA14 antibody, 1110014P06Rik antibody, PGEA14 antibody, Pgea1 antibody, chibby homolog 1 S homeolog antibody, chibby homolog 1 antibody, chibby family member 1, beta catenin antagonist antibody, cby1.S antibody, cby1 antibody, CBY1 antibody, Cby1 antibody

Background: Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.

Molecular Weight: 14470

Gene ID: 25776

NCBI Accession: NP_001002880, NP_056188

UniProt: Q9Y3M2