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Details for Product No. ABIN653274

Inositol-Trisphosphate 3-Kinase C (ITPKC) (N-Term), (AA 89-117) antibody

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Antigen
Synonyms IP3-3KC, IP3KC, 9130023N17Rik, fi30c01, itpkc, wu:fi30c01
Epitope
»Alternatives N-Term, AA 89-117
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN653274
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 AA from the N-terminal region of human ITPKC.
Clone RB23817
Isotype Ig
Specificity This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96~125 amino acids from the N-terminal region of human ITPKC.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ITPKC
Background ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.
Synonyms: Inositol 1,4,5-trisphosphate 3-kinase C, InsP 3-kinase C, IP3 3-kinase C, IP3K C, Inositol-trisphosphate 3-kinase C, IP3KC, ITPKC
Molecular Weight 75207 DA
Gene ID 80271
UniProt Q96DU7
Research Area Cancer, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Nalaskowski, Windhorst, Stockebrand et al.: "Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains." in: Biological chemistry, Vol. 387, Issue 5, pp. 583-93, 2006 (PubMed).

Onouchi, Gunji, Burns et al.: "ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms." in: Nature genetics, Vol. 40, Issue 1, pp. 35-42, 2007 (PubMed).

Chi, Huang, Chen et al.: "ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children." in: Human molecular genetics, Vol. 19, Issue 6, pp. 1147-51, 2010 (PubMed).

Alternatives for antigen "Inositol-Trisphosphate 3-Kinase C (ITPKC)", type "Antibodies"
Hosts (13), (5), (3)
Reactivities (21)
Applications (20), (12), (3), (2), (2), (2), (2)
Epitopes (5), (3), (2), (2), (1), (1)
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