UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2) (N-Term), (AA 26-53) antibody

Details for Product No. ABIN653281
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Antigen
Synonyms AI480629, GalNAc-T2
Epitope
N-Term, AA 26-53
(8), (8), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(17), (1)
Host
Rabbit
(15), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(17), (9), (9), (7), (6), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN653281
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Immunogen This GALNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 AA from the N-terminal region of human GALNT2.
Clone RB23942
Isotype Ig
Specificity This GALNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32~62 amino acids from the N-terminal region of human GALNT2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GALNT2
Background GALNT2 encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.
Synonyms: Polypeptide N-acetylgalactosaminyltransferase 2 soluble form, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2, Protein-UDP acetylgalactosaminyltransferase 2, Polypeptide GalNAc transferase 2, pp-GaNTase 2, GalNAc-T2, Polypeptide N-acetylgalactosaminyltransferase 2, GALNT2
Molecular Weight 64733 DA
Gene ID 2590
UniProt Q10471
Research Area Cancer, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2) (N-Term), (AA 26-53) antibody Western blot analysis of GALNT2 Antibody (N-term) (ABIN653281) in Hela cell line lysates (35 µg/lane). GALNT2 (arrow) was detected using the purified polyclonal antibody.
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2) (N-Term), (AA 26-53) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue reacted with GALNT2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2) (N-Term), (AA 26-53) antibody (3) GALNT2 Antibody (N-term) (ABIN653281) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Nakayama, Bayasgalan, Yamanaka et al.: "Large scale replication analysis of loci associated with lipid concentrations in a Japanese population." in: Journal of medical genetics, Vol. 46, Issue 6, pp. 370-4, 2009 (PubMed).

Hegele, Ban, Hsueh et al.: "A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4189-94, 2009 (PubMed).

Weissglas-Volkov, Aguilar-Salinas, Sinsheimer et al.: "Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples." in: Circulation. Cardiovascular genetics, Vol. 3, Issue 1, pp. 31-8, 2010 (PubMed).

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