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Details for Product No. ABIN653356

Diaphanous Homolog 2 (Drosophila) (DIAPH2) (AA 870-899), (Center) antibody

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Antigen
Synonyms Diap2, RGD1564399, DIA, DIA2, DRF2, POF, POF2, Dia3, Diaph2, Drf2, E430022I22Rik, DIAPH2, MGC148327, dia2, sb:eu1025, si:dkeyp-11a1.1
Epitope
»Alternatives AA 870-899, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN653356
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This DIAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 870-899 AA from the Central region of human DIAPH2.
Clone RB23866
Isotype Ig
Specificity This DIAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 877~907 amino acids from the Central region of human DIAPH2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DIAPH2
Background DIAPH2 belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this protein have been linked to premature ovarian failure 2.
Synonyms: Diaphanous-related formin-2, DRF2, Protein diaphanous homolog 2, DIA, DIAPH2
Molecular Weight 125569 DA
Gene ID 1730
UniProt O60879
Research Area Signaling, Protein Modifications, Cancer, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Satoh, Tominaga: "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 39290-4, 2001 (PubMed).

Gasman, Kalaidzidis, Zerial: "RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase." in: Nature cell biology, Vol. 5, Issue 3, pp. 195-204, 2003 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Alternatives for antigen "Diaphanous Homolog 2 (Drosophila) (DIAPH2)", type "Antibodies"
Hosts (21)
Reactivities (21), (12), (2), (1)
Applications (12), (10), (6), (5), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1), (1)
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