anti-Complexin 1 antibody (CPLX1) (AA 33-60)

Details for Product anti-CPLX1 Antibody No. ABIN653361
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AA 33-60, Center
(16), (13), (6), (1)
(39), (18), (17)
(34), (4), (1), (1)
Clonality (Clone)
Polyclonal ()
This Complexin 1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(29), (19), (14), (10), (5), (3), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
Shipping to United States ( )
Availability Please contact our customer support.
Immunogen This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 AA from the Central region of human CPLX1.
Clone RB23961
Isotype Ig
Specificity This CPLX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39~69 amino acids from the Central region of human CPLX1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CPLX1 (CPLX1 Antibody Abstract)
Background CPLX1 encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.
Synonyms: Synaphin-2, Complexin I, CPX I, Complexin-1, CPLX1
Molecular Weight 15030 DA
Gene ID 10815
UniProt O14810
Research Area Neurology
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.32 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Complexin 1 antibody (CPLX1) (AA 33-60) (ABIN653361) Western blot analysis of CPLX1 Antibody (Center) (ABIN653361) in mouse brain tissue l...
Immunohistochemistry (IHC) image for anti-Complexin 1 antibody (CPLX1) (AA 33-60) (ABIN653361) Formalin-fixed and paraffin-embedded human brain tissue reacted with CPLX1 Antibody (...
Background publications Giraudo, Eng, Melia et al.: "A clamping mechanism involved in SNARE-dependent exocytosis." in: Science (New York, N.Y.), Vol. 313, Issue 5787, pp. 676-80, 2006 (PubMed).

Chen, Tomchick, Kovrigin et al.: "Three-dimensional structure of the complexin/SNARE complex." in: Neuron, Vol. 33, Issue 3, pp. 397-409, 2002 (PubMed).

Catalog No. ABIN653361
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