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Details for Product No. ABIN653429

Chromosome 11 Open Reading Frame 30 (C11orf30) (N-Term), (AA 46-75) antibody

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Antigen
Synonyms EMSY, 2310016L09Rik, AU019521, AU019557, Emsy, 2210018M11RIK
Epitope
»Alternatives N-Term, AA 46-75
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN653429
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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anti-Chromosome 11 Open Reading Frame 30 (C11orf30) (N-Term), (AA 46-75) antibody

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 AA from the N-terminal region of human C11orf30.
Clone RB23056
Isotype Ig
Specificity This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53~83 amino acids from the N-terminal region of human C11orf30.
Predicted Reactivity Mouse (Murine),Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name C11orf30
Background Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.
Synonyms: Protein EMSY, GL002, C11orf30, EMSY
Molecular Weight 141468 DA
Gene ID 56946
UniProt Q7Z589
Research Area Cancer, Transcription Factors, Signaling, Cell Structure

Application Details

Target Details Handling Images References Alternatives back to top
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only

Handling

Target Details Application Details Images References Alternatives back to top
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References

Target Details Application Details Handling Images Alternatives back to top
Background publications Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

Mavaddat, Dunning, Ponder et al.: "Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 1, pp. 255-9, 2009 (PubMed).

Garapaty, Xu, Trojer et al.: "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7542-52, 2009 (PubMed).

Esparza-Gordillo, Weidinger, Fölster-Holst et al.: "A common variant on chromosome 11q13 is associated with atopic dermatitis." in: Nature genetics, Vol. 41, Issue 5, pp. 596-601, 2009 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "Chromosome 11 Open Reading Frame 30 (C11orf30)", type "Antibodies"
Hosts (20), (2)
Reactivities (22), (13), (12), (12), (12)
Applications (12), (10), (6), (4), (3), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1), (1)
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