Chromosome 11 Open Reading Frame 30 (C11orf30) (N-Term), (AA 46-75) antibody

Details for Product No. ABIN653429
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Antigen
Epitope
N-Term, AA 46-75
(8), (8), (3), (2), (1), (1), (1)
Reactivity
Human
(31), (13), (12), (12), (12)
Host
Rabbit
(29), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(21), (10), (9), (5), (5), (2), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 400 μL
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Catalog No. ABIN653429
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Immunogen This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 AA from the N-terminal region of human C11orf30.
Clone RB23056
Isotype Ig
Specificity This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53~83 amino acids from the N-terminal region of human C11orf30.
Predicted Reactivity Mouse (Murine),Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name C11orf30
Background Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.
Synonyms: Protein EMSY, GL002, C11orf30, EMSY
Molecular Weight 141468 DA
Gene ID 56946
UniProt Q7Z589
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Chromosome 11 Open Reading Frame 30 (C11orf30) (N-Term), (AA 46-75) antibody Western blot analysis of C11orf30 Antibody (N-term) (ABIN653429) in Ramos cell line lysates (35 µg/lane). C11orf30 (arrow) was detected using the purified polyclonal antibody.
Background publications Esparza-Gordillo, Weidinger, Fölster-Holst et al.: "A common variant on chromosome 11q13 is associated with atopic dermatitis." in: Nature genetics, Vol. 41, Issue 5, pp. 596-601, 2009 (PubMed).

Garapaty, Xu, Trojer et al.: "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7542-52, 2009 (PubMed).

Mavaddat, Dunning, Ponder et al.: "Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 1, pp. 255-9, 2009 (PubMed).

Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

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