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Hairy and Enhancer of Split 7 (Drosophila) (HES7) (N-Term), (AA 26-55) antibody

Details for Product No. ABIN653667
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Antigen
Epitope
N-Term, AA 26-55
(9), (8), (4), (2)
Reactivity
Human, Mouse (Murine)
(26), (19), (14), (14), (13), (13)
Host
Rabbit
(26), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(18), (10), (9), (3), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN653667
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Immunogen This HES7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 AA from the N-terminal region of human HES7.
Clone RB24049
Isotype Ig
Specificity This HES7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33~63 amino acids from the N-terminal region of human HES7.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HES7
Background HES7 is a member of the hairy and enhancer of split family of bHLH transcription factors. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton.
Synonyms: Class B basic helix-loop-helix protein 37, bHLHb37, bHLH factor Hes7, Hairy and enhancer of split 7, Transcription factor HES-7, hHes7, BHLHB37, HES7
Molecular Weight 24894 DA
Gene ID 84667
UniProt Q9BYE0
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Hairy and Enhancer of Split 7 (Drosophila) (HES7) (N-Term), (AA 26-55) antibody Western blot analysis of HES7 Antibody (N-term) (ABIN653667) in mouse heart tissue lysates (35 µg/lane). HES7 (arrow) was detected using the purified polyclonal antibody.
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Sparrow, Guillén-Navarro, Fatkin et al.: "Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis." in: Human molecular genetics, Vol. 17, Issue 23, pp. 3761-6, 2008 (PubMed).

Validation Images
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