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Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (C-Term), (AA 665-692) antibody

Details for Product No. ABIN653787
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Antigen
Synonyms trabid, zranb1, zgc:154177, TRABID, 9330160G10Rik, D7Wsu87e, Gm1956, Trabid
Epitope
C-Term, AA 665-692
(13), (8), (1), (1)
Reactivity
Human, Mouse (Murine)
(17), (4), (2), (2), (2)
Host
Rabbit
(13), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(18), (11), (7), (2)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN653787
291.50 $
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Immunogen This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 AA from the C-terminal region of human ZRANB1.
Clone RB23203
Isotype Ig
Specificity This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672~701 amino acids from the C-terminal region of human ZRANB1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ZRANB1
Background ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
Synonyms: hTrabid, Zinc finger Ran-binding domain-containing protein 1, Ubiquitin thioesterase ZRANB1,TRABID, ZRANB1
Molecular Weight 80967 DA
Gene ID 54764
UniProt Q9UGI0
Research Area Signaling, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (C-Term), (AA 665-692) antibody Western blot analysis of ZRANB1 Antibody (C-term) (ABIN653787) in K562 cell line lysates (35 µg/lane). ZRANB1 (arrow) was detected using the purified polyclonal antibody.
anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (C-Term), (AA 665-692) antibody (2) Western blot analysis of ZRANB1 Antibody (C-term) (ABIN653787) in mouse cerebellum tissue lysates (35 µg/lane). ZRANB1 (arrow) was detected using the purified polyclonal antibody.
anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (C-Term), (AA 665-692) antibody (3) ZRANB1 Antibody (C-term) (ABIN653787) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Tran, Hamada, Schwarz-Romond et al.: "Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains." in: Genes & development, Vol. 22, Issue 4, pp. 528-42, 2008 (PubMed).

Validation Images
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