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Details for Product No. ABIN653842

UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody

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Antigen
Synonyms B3Gn-T6, BGnT-6, beta-1,3-Gn-T6, beta3Gn-T6, BC039789, Core-3, Core3
Epitope
»Alternatives AA 146-173, Center
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN653842
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 AA from the Central region of human B3GNT6.
Clone RB24269
Isotype Ig
Specificity This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152~182 amino acids from the Central region of human B3GNT6.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name B3GNT6
Background Synonyms: Core 3 synthase, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-Gn-T6, Beta3Gn-T6, BGnT-6,B3GNT6
Molecular Weight 42748 DA
Gene ID 192134
UniProt Q6ZMB0
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Iwai, Inaba, Naundorf et al.: "Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12802-9, 2002 (PubMed).

Iwai, Kudo, Kawamoto et al.: "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4572-7, 2005 (PubMed).

Lee, Hatakeyama, Yu et al.: "Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex." in: The Journal of biological chemistry, Vol. 284, Issue 25, pp. 17157-69, 2009 (PubMed).

Alternatives for antigen "UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6)", type "Antibodies"
Hosts (2), (1)
Reactivities (3), (2)
Applications (3), (1), (1), (1), (1)
Epitopes (1), (1), (1), (1)
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