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UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody

Details for Product No. ABIN653842, Supplier: Login to see
Antigen
  • B3Gn-T6
  • BGnT-6
  • beta-1,3-Gn-T6
  • beta3Gn-T6
  • BC039789
  • Core-3
  • Core3
Epitope
AA 146-173, Center
15
14
8
3
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
23
3
Host
Rabbit
19
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
20
16
14
1
1
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Immunogen This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 AA from the Central region of human B3GNT6.
Clone RB24269
Isotype Ig
Specificity This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152~182 amino acids from the Central region of human B3GNT6.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name B3GNT6 (B3GNT6 Antibody Abstract)
Background Synonyms: Core 3 synthase, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-Gn-T6, Beta3Gn-T6, BGnT-6,B3GNT6
Molecular Weight 42748 DA
Gene ID 192134
UniProt Q6ZMB0
Research Area Cell Signaling, Cell Structure, Protein Modifications
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody (ABIN653842) Western blot analysis of B3GNT6 Antibody (Center) (ABIN653842) in mouse brain tissue ...
Immunohistochemistry (IHC) image for anti-UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody (ABIN653842) B3GNT6 Antibody (Center) (ABIN653842) immunohistochemistry analysis in formalin fixed...
Background publications Lee, Hatakeyama, Yu et al.: "Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex." in: The Journal of biological chemistry, Vol. 284, Issue 25, pp. 17157-69, 2009 (PubMed).

Iwai, Kudo, Kawamoto et al.: "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4572-7, 2005 (PubMed).

Iwai, Inaba, Naundorf et al.: "Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12802-9, 2002 (PubMed).

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