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UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody

Details for Product No. ABIN653842
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Antigen
Synonyms B3Gn-T6, BGnT-6, beta-1,3-Gn-T6, beta3Gn-T6, BC039789, Core-3, Core3
Epitope
AA 146-173, Center
(7), (6), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(10), (2)
Host
Rabbit
(9), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(10), (7), (7), (1), (1)
Pubmed 3 references available
Quantity 400 µL
Options
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Catalog No. ABIN653842
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 AA from the Central region of human B3GNT6.
Clone RB24269
Isotype Ig
Specificity This B3GNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152~182 amino acids from the Central region of human B3GNT6.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name B3GNT6
Background Synonyms: Core 3 synthase, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-N-acetylglucosaminyltransferase 6, Beta-1,3-Gn-T6, Beta3Gn-T6, BGnT-6,B3GNT6
Molecular Weight 42748 DA
Gene ID 192134
UniProt Q6ZMB0
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody Western blot analysis of B3GNT6 Antibody (Center) (ABIN653842) in mouse brain tissue lysates (35 µg/lane). B3GNT6 (arrow) was detected using the purified polyclonal antibody.
anti-UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (AA 146-173), (Center) antibody (2) B3GNT6 Antibody (Center) (ABIN653842) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Iwai, Inaba, Naundorf et al.: "Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12802-9, 2002 (PubMed).

Iwai, Kudo, Kawamoto et al.: "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4572-7, 2005 (PubMed).

Lee, Hatakeyama, Yu et al.: "Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex." in: The Journal of biological chemistry, Vol. 284, Issue 25, pp. 17157-69, 2009 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN653842
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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