Methyltransferase Like 1 (METTL1) (AA 147-175), (Center) antibody

Details for Product No. ABIN653843
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Antigen
Synonyms Dmel\\CG4045, EG:22E5.4, C12orf1, TRM8, TRMT8, YDL201w, 2810012D02Rik
Epitope
AA 147-175, Center
(8), (8), (4), (3), (1), (1), (1)
Reactivity
Human
(23), (6), (6), (1)
Host
Rabbit
(20), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(19), (14), (3), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN653843
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Immunogen This METTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 AA from the Central region of human METTL1.
Clone RB24424
Isotype Ig
Specificity This METTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154~183 amino acids from the Central region of human METTL1.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name METTL1
Background This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.
Synonyms: Methyltransferase-like protein 1, tRNA(m7G46)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase,C12orf1, METTL1
Molecular Weight 31471 DA
Gene ID 4234
UniProt Q9UBP6
Research Area Translation Factors, Signaling, Phospho-specific antibodies, Stem Cells, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Methyltransferase Like 1 (METTL1) (AA 147-175), (Center) antibody Western blot analysis of METTL1 Antibody (Center) (ABIN653843) in Ramos cell line lysates (35 µg/lane). METTL1 (arrow) was detected using the purified polyclonal antibody.
Background publications Cartlidge, Knebel, Peggie et al.: "The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells." in: The EMBO journal, Vol. 24, Issue 9, pp. 1696-705, 2005 (PubMed).

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