ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody

Details for Product No. ABIN654102
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Antigen
Synonyms EST182763, MRP7, SIMRP7, Mrp7, mFLJ00002, 6230418K12Rik, Abcc10, C130009K11Rik, OM-1, Om1, Ranbp8
Epitope
AA 767-793, Center
(23), (16), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(78), (13), (13), (1)
Host
Rabbit
(55), (15), (5), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (42), (21), (16), (10), (6), (3), (3), (3), (3), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Immunogen This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 AA from the Central region of human ABCC10.
Clone RB22383
Isotype Ig
Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC10 (ABCC10 Antibody Abstract)
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Multidrug resistance-associated protein 7,ABCC10,MRP7, SIMRP7
Molecular Weight 161629 DA
Gene ID 89845
NCBI Accession NP_258261
UniProt Q5T3U5
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Signaling, Chromatin
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody ABCC10 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane...
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (2) ABCC10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffi...
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (3) ABCC10 Antibody (Center) flow cytometric analysis of HepG2 cells (right histogram) c...
Background publications Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).

Validation Images
Catalog No. ABIN654102
291.50 $
Plus shipping costs $45.00
Quantity
Price
400 μL
291.50 $

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