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Details for Product No. ABIN654102

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody

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Antigen
Synonyms MRP7, SIMRP7, EST182763, Om1, OM-1, Abcc10, Ranbp8, 6230418K12Rik, C130009K11Rik, Mrp7, mFLJ00002
Epitope
»Alternatives AA 767-793, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN654102
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 AA from the Central region of human ABCC10.
Clone RB22383
Isotype Ig
Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC10
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Multidrug resistance-associated protein 7,ABCC10,MRP7, SIMRP7
Molecular Weight 161629 DA
Gene ID 89845
UniProt Q5T3U5, NP_258261.2
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Signaling, Chromatin
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).

Alternatives for antigen "ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10)", type "Antibodies"
Hosts (30), (5), (4), (2)
Reactivities (39), (12), (12), (12), (12), (12), (12)
Applications (29), (20), (10), (6), (4), (4), (4), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (3), (2), (2), (1), (1)
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