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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody

Details for Product No. ABIN654102
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Antigen
Synonyms MRP7, SIMRP7, EST182763, Om1, OM-1, Abcc10, Ranbp8, 6230418K12Rik, C130009K11Rik, Mrp7, mFLJ00002
Epitope
AA 767-793, Center
(13), (8), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(50), (12), (12), (12), (12), (12), (12)
Host
Rabbit
(42), (4), (3), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(39), (27), (12), (10), (10), (6), (4), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN654102
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 AA from the Central region of human ABCC10.
Clone RB22383
Isotype Ig
Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC10
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Multidrug resistance-associated protein 7,ABCC10,MRP7, SIMRP7
Molecular Weight 161629 DA
Gene ID 89845
UniProt Q5T3U5, NP_258261.2
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Signaling, Chromatin
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody ABCC10 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ABCC10 antibody detected the ABCC10 protein (arrow).
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (2) ABCC10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (3) ABCC10 Antibody (Center) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN654102
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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