Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 81-107), (Center) antibody

Details for Product No. ABIN654106
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Antigen
Synonyms fj66g02, zgc:73157, wu:fj66g02, Bcatc, BCATC, BCT1, ECA39, MECA39, PNAS121, PP18, BCATc, Eca39
Epitope
AA 81-107, Center
(8), (7), (5), (4), (2), (2), (1), (1)
Reactivity
Human
(37), (20), (16), (13), (12), (12), (12), (2)
Host
Rabbit
(36), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(29), (15), (13), (10), (6), (1)
Pubmed 1 reference available
Quantity 400 µL
Options
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Catalog No. ABIN654106
291.50 $
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Immunogen This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 AA from the Central region of human BCAT1.
Clone RB22413
Isotype Ig
Specificity This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the Central region of human BCAT1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCAT1
Background This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
Synonyms: Branched-chain-amino-acid aminotransferase, cytosolic,BCAT1,BCT1, ECA39
Molecular Weight 42966 DA
Gene ID 586
NCBI Accession NP_005495, NP_001171563, NP_001171562, NP_001171565, NP_001171564
UniProt P54687
Research Area Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 81-107), (Center) antibody BCAT1 Antibody (Center) (ABIN654106) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Eijgelsheim, Newton-Cheh, Sotoodehnia et al.: "Genome-wide association analysis identifies multiple loci related to resting heart rate." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3885-94, 2010 (PubMed).

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