DIS3 Mitotic Control Homolog (S. Cerevisiae) (DIS3) (AA 295-323), (Center) antibody

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Antigen
Epitope
AA 295-323, Center
(8), (5), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(33), (15), (14), (12), (1)
Host
Rabbit
(30), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(24), (12), (9), (8), (5), (3), (3), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN654155
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Immunogen This DIS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-323 AA from the Central region of human DIS3.
Clone RB24091
Isotype Ig
Specificity This DIS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the Central region of human DIS3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DIS3
Background Synonyms: Exosome complex exonuclease RRP44,DIS3,KIAA1008, RRP44
Molecular Weight 109003 DA
Gene ID 22894
NCBI Accession NP_001121698, NP_055768
UniProt Q9Y2L1
Research Area Signaling, Protein Modifications, Transcription Factors, Chromatin, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-DIS3 Mitotic Control Homolog (S. Cerevisiae) (DIS3) (AA 295-323), (Center) antibody DIS3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the DIS3 antibody detected DIS3 protein (arrow).
anti-DIS3 Mitotic Control Homolog (S. Cerevisiae) (DIS3) (AA 295-323), (Center) antibody (2) DIS3 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DIS3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Background publications Leung, Andersen, Mann et al.: "Bioinformatic analysis of the nucleolus." in: The Biochemical journal, Vol. 376, Issue Pt 3, pp. 553-69, 2003 (PubMed).

Andersen, Lam, Leung et al.: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, 2005 (PubMed).

Tomecki, Kristiansen, Lykke-Andersen et al.: "The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L." in: The EMBO journal, Vol. 29, Issue 14, pp. 2342-57, 2010 (PubMed).

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