MAF1 Homolog (S. Cerevisiae) (MAF1) (AA 90-117), (Center) antibody

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Synonyms 1110068E11Rik, AU042856, maf1
AA 90-117, Center
(16), (9), (7), (2), (2), (2), (1), (1), (1)
Human, Mouse (Murine)
(34), (7), (3), (1)
(31), (4)
Clonality (Clone)
Polyclonal ()
(3), (3), (3), (2), (2), (2)
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(31), (18), (17), (16), (4), (4), (3), (2), (1), (1)
Pubmed 4 references available
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This MAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 AA from the Central region of human MAF1.
Clone RB24238
Isotype Ig
Specificity This MAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the Central region of human MAF1.
Predicted Reactivity Cow (Bovine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAF1 (MAF1 Antibody Abstract)
Background This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
Synonyms: Repressor of RNA polymerase III transcription MAF1 homolog,MAF1,
Molecular Weight 28771 DA
Gene ID 84232
NCBI Accession NP_115648
UniProt Q9H063
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-MAF1 Homolog (S. Cerevisiae) (MAF1) (AA 90-117), (Center) antibody (ABIN654163) MAF1 antibody (Center) (ABIN654163) immunohistochemistry analysis in formalin fixed a...
Product cited in: Rohira, Chen, Allen et al.: "Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 19288-95, 2013 (PubMed).

Background publications Kantidakis, Ramsbottom, Birch et al.: "mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 26, pp. 11823-8, 2010 (PubMed).

Shor, Wu, Shakey et al.: "Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 15380-92, 2010 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Catalog No. ABIN654163
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