WFDC12 antibody (WAP Four-Disulfide Core Domain 12) (AA 66-94)

Details for Product anti-WFDC12 Antibody No. ABIN654327, Supplier: Log in to see
  • C20orf122
  • SWAM2
  • WAP2
  • dJ211D12.4
  • Swam2
  • WAP four-disulfide core domain 12
  • WFDC12
  • Wfdc12
AA 66-94, C-Term
Clonality (Clone)
Polyclonal ()
This WFDC12 antibody is un-conjugated
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Immunogen This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 AA from the C-terminal region of human WFDC12.
Clone RB27994
Isotype Ig
Specificity This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the C-terminal region of human WFDC12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name WFDC12 (WFDC12 Antibody Abstract)
Background This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Synonyms: WAP four-disulfide core domain protein 12,WFDC12,C20orf122, WAP2
Molecular Weight 12050 DA
Gene ID 128488
NCBI Accession NP_543145
UniProt Q8WWY7
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.33 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-WFDC12 antibody (WAP Four-Disulfide Core Domain 12) (AA 66-94) (ABIN654327) WFDC12 antibody (C-term) (ABIN654327) immunohistochemistry analysis in formalin fixed...
Background publications Clauss, Lilja, Lundwall: "The evolution of a genetic locus encoding small serine proteinase inhibitors." in: Biochemical and biophysical research communications, Vol. 333, Issue 2, pp. 383-9, 2005 (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Clauss, Lilja, Lundwall: "A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein." in: The Biochemical journal, Vol. 368, Issue Pt 1, pp. 233-42, 2002 (PubMed).

Lundwall, Clauss: "Identification of a novel protease inhibitor gene that is highly expressed in the prostate." in: Biochemical and biophysical research communications, Vol. 290, Issue 1, pp. 452-6, 2002 (PubMed).