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Details for Product No. ABIN654327

WAP Four-Disulfide Core Domain 12 (WFDC12) (C-Term), (AA 66-94) antibody

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Antigen
Synonyms Swam2, WAP2, C20orf122, SWAM2, dJ211D12.4
Epitope
»Alternatives C-Term, AA 66-94
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 5 references available
Catalog no. ABIN654327
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 AA from the C-terminal region of human WFDC12.
Clone RB27994
Isotype Ig
Specificity This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the C-terminal region of human WFDC12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name WFDC12
Background This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Synonyms: WAP four-disulfide core domain protein 12,WFDC12,C20orf122, WAP2
Molecular Weight 12050 DA
Gene ID 128488
UniProt Q8WWY7, NP_543145.1
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.33 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Lundwall, Clauss: "Identification of a novel protease inhibitor gene that is highly expressed in the prostate." in: Biochemical and biophysical research communications, Vol. 290, Issue 1, pp. 452-6, 2002 (PubMed).

Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Clauss, Lilja, Lundwall: "A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein." in: The Biochemical journal, Vol. 368, Issue Pt 1, pp. 233-42, 2002 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Clauss, Lilja, Lundwall: "The evolution of a genetic locus encoding small serine proteinase inhibitors." in: Biochemical and biophysical research communications, Vol. 333, Issue 2, pp. 383-9, 2005 (PubMed).

Alternatives for antigen "WAP Four-Disulfide Core Domain 12 (WFDC12)", type "Antibodies"
Hosts (3)
Reactivities (3)
Applications (3), (3), (2), (2), (1)
Epitopes (3), (2), (1)
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