Folate Receptor 1 (Adult) (FOLR1) (N-Term), (AA 33-68) antibody

Details for Product No. ABIN654650
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Antigen
Epitope
N-Term, AA 33-68
(8), (7), (7), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(39), (27), (15), (14)
Host
Rabbit
(37), (17), (14), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(5), (4), (2), (2), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(51), (47), (15), (10), (7), (7), (6), (4), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN654650
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Immunogen This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 AA from the N-terminal region of human FOLR1.
Clone RB28535
Isotype Ig
Specificity This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-542 amino acids from the N-terminal region of human FOLR1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOLR1
Background The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Synonyms: Folate receptor alpha,FOLR1,FOLR
Molecular Weight 29819 DA
Gene ID 2348
NCBI Accession NP_000793
UniProt P15328
Research Area Cell Signaling, Protein Modifications, Cell Structure, Neurology
Application Notes WB = 1:1000, IHC = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Folate Receptor 1 (Adult) (FOLR1) (N-Term), (AA 33-68) antibody FOLR1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FOLR1 antibody detected the FOLR1 protein (arrow).
anti-Folate Receptor 1 (Adult) (FOLR1) (N-Term), (AA 33-68) antibody (2) FOLR1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FOLR1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-Folate Receptor 1 (Adult) (FOLR1) (N-Term), (AA 33-68) antibody (3) FOLR1 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

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