B-Cell CLL/lymphoma 7A (BCL7A) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN654937
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Antigen
Epitope
N-Term, AA 1-30
(8), (8), (7), (4), (3), (1)
Reactivity
Human
(30), (9), (1), (1), (1), (1)
Host
Rabbit
(23), (7)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (16)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN654937
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Immunogen This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human BCL7A.
Clone RB24969
Isotype Ig
Specificity This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A.
Predicted Reactivity Mouse (Murine),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCL7A
Background This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: B-cell CLL/lymphoma 7 protein family member A,BCL7A,
Molecular Weight 22810 DA
Gene ID 605
NCBI Accession NP_066273, NP_001019979
UniProt Q4VC05
Research Area Phospho-specific antibodies, Protein Modifications, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-B-Cell CLL/lymphoma 7A (BCL7A) (N-Term), (AA 1-30) antibody BCL7A Antibody (N-term) (ABIN654937) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the BCL7A antibody detected the BCL7A protein (arrow).
Background publications Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

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