CUB and Zona Pellucida-Like Domains 1 (CUZD1) (C-Term), (AA 579-607) antibody

Details for Product No. ABIN655091
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Antigen
Synonyms ERG-1, UO-44, Erg-1, Itmap1, Uo-44, Usg, Utczp, ERG1, Uo
Epitope
C-Term, AA 579-607
(9), (8), (2), (1), (1), (1)
Reactivity
Human
(12), (1), (1)
Host
Rabbit
(13), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(14), (10), (10), (8), (5), (4), (4), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN655091
238.50 $
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Immunogen This CUZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 579-607 AA from the C-terminal region of human CUZD1.
Clone RB24983
Isotype Ig
Specificity This CUZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-614 amino acids from the C-terminal region of human CUZD1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CUZD1
Background Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
Synonyms: CUB and zona pellucida-like domain-containing protein 1,CUZD1,
Molecular Weight 68153 DA
Gene ID 50624
NCBI Accession NP_071317
UniProt Q86UP6
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (C-Term), (AA 579-607) antibody Confocal immunofluorescent analysis of CUZD1 Antibody (C-term) with 293 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (C-Term), (AA 579-607) antibody (2) CUZD1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CUZD1 antibody detected the CUZD1 protein (arrow).
anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (C-Term), (AA 579-607) antibody (3) CUZD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancrease tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CUZD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Leong, Ong, Tay et al.: "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro." in: Oncogene, Vol. 26, Issue 6, pp. 870-80, 2007 (PubMed).

Validation Images
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