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Details for Product No. ABIN655194

Testis Specific Serine Kinase 4 (TSSK4) (C-Term), (AA 226-254) antibody

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Antigen
Synonyms 1700020B19Rik, 4933424F08Rik, TSK-4, TSSK-4, C14orf20, STK22E, TSK4, TSSK5
Epitope
»Alternatives C-Term, AA 226-254
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN655194
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 AA from the C-terminal region of human TSSK4.
Clone RB27979
Isotype Ig
Specificity This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the C-terminal region of human TSSK4.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TSSK4
Background This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.
Synonyms: TSSK4,Testis-specific serine/threonine-protein kinase 4,C14orf20, STK22E, TSSK5
Molecular Weight 37454 DA
Gene ID 283629
UniProt NP_777604.2, Q6SA08
Research Area Cell Structure, Signaling, Protein Modifications, Cell Cycle, Cell Signaling, Chromatin, Phospho-specific antibodies
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Chen, Lin, Wei et al.: "TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway." in: Biochemical and biophysical research communications, Vol. 333, Issue 3, pp. 742-9, 2005 (PubMed).

Aston, Krausz, Laface et al.: "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent." in: Human reproduction (Oxford, England), Vol. 25, Issue 6, pp. 1383-97, 2010 (PubMed).

Alternatives for antigen "Testis Specific Serine Kinase 4 (TSSK4)", type "Antibodies"
Hosts (14)
Reactivities (14), (8)
Applications (14), (9), (3), (2), (2), (1)
Epitopes (4), (3), (2), (1)
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