Testis Specific Serine Kinase 4 (TSSK4) (C-Term), (AA 226-254) antibody

Details for Product No. ABIN655194
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Antigen
Synonyms C14orf20, STK22E, TSK-4, TSK4, TSSK5, 1700020B19Rik, 4933424F08Rik, TSSK-4, RGD1560814
Epitope
C-Term, AA 226-254
(8), (8), (6), (1), (1), (1), (1)
Reactivity
Human
(24), (11)
Host
Rabbit
(24)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(24), (19), (7), (7), (3), (2)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN655194
291.50 $
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Immunogen This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 AA from the C-terminal region of human TSSK4.
Clone RB27979
Isotype Ig
Specificity This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the C-terminal region of human TSSK4.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TSSK4
Background This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.
Synonyms: TSSK4,Testis-specific serine/threonine-protein kinase 4,C14orf20, STK22E, TSSK5
Molecular Weight 37454 DA
Gene ID 283629
NCBI Accession NP_777604
UniProt Q6SA08
Research Area Cell Structure, Signaling, Protein Modifications, Cell Cycle, Cell Signaling, Chromatin, Phospho-specific antibodies
Application Notes WB = 1:1000, IHC = 1:50-100, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Testis Specific Serine Kinase 4 (TSSK4) (C-Term), (AA 226-254) antibody TSSK4 Antibody (C-term) (ABIN655194) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Chen, Lin, Wei et al.: "TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway." in: Biochemical and biophysical research communications, Vol. 333, Issue 3, pp. 742-9, 2005 (PubMed).

Aston, Krausz, Laface et al.: "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent." in: Human reproduction (Oxford, England), Vol. 25, Issue 6, pp. 1383-97, 2010 (PubMed).

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