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COPE antibody (Coatomer Protein Complex, Subunit epsilon) (AA 273-300)

Details for Product anti-COPE Antibody No. ABIN655276, Supplier: Login to see New
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Antigen
Synonyms COPE, DDBDRAFT_0189670, DDBDRAFT_0233799, DDB_0189670, DDB_0233799, DKFZp469K1716, MGC80063, MGC130714, epsilon-COP, 1110005D17Rik, Cope1
Epitope
AA 273-300, C-Term
(16), (15), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(35), (4), (3)
Host
Rabbit
(32), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
This COPE antibody is un-conjugated
(2), (2), (2), (2), (2), (1)
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(32), (22), (19), (10), (6), (2), (1)
Pubmed 2 references available
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Quantity 400 μL
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Immunogen This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 AA from the C-terminal region of human COPE.
Clone RB19580
Isotype Ig
Specificity This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-308 amino acids from the C-terminal region of human COPE.
Predicted Reactivity Chicken,Hamster,Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name COPE (COPE Antibody Abstract)
Background The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: Coatomer subunit epsilon,COPE,
Molecular Weight 34482 Da
Gene ID 11316
UniProt O14579
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-COPE antibody (Coatomer Protein Complex, Subunit epsilon) (AA 273-300) (ABIN655276) COPE Antibody (C-term) (ABIN655276) immunohistochemistry analysis in formalin fixed a...
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Morikawa, Aoki, Kano et al.: "Intracellular phospholipase A1gamma (iPLA1gamma) is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26620-30, 2009 (PubMed).

Catalog No. ABIN655276
$324.50
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