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Details for Product No. ABIN655558

Killin, p53-Regulated DNA Replication Inhibitor (KLLN) (C-Term), (AA 136-163) antibody

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Antigen
Synonyms CWS4, KILLIN
Epitope
»Alternatives C-Term, AA 136-163
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN655558
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 AA from the C-terminal region of human KILLIN.
Clone RB29503
Isotype Ig
Specificity This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the C-terminal region of human KILLIN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KILLIN
Background DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
Synonyms: Killin
Molecular Weight 19958 DA
Gene ID 100144748
UniProt B2CW77, NP_001119521.1
Research Area Apoptosis/Necrosis, Cell Structure, Signaling, Transcription Factors
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Cho, Liang: "Killin is a p53-regulated nuclear inhibitor of DNA synthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 14, pp. 5396-401, 2008 (PubMed).

Alternatives for antigen "Killin, p53-Regulated DNA Replication Inhibitor (KLLN)", type "Antibodies"
Hosts (14)
Reactivities (14)
Applications (9), (5), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (1)
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