Killin, p53-Regulated DNA Replication Inhibitor (KLLN) (C-Term), (AA 136-163) antibody

Details for Product No. ABIN655558
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Antigen
Synonyms CWS4, KILLIN
Epitope
C-Term, AA 136-163
(2), (2), (1)
Reactivity
Human
(14)
Host
Rabbit
(14)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(9), (5), (3), (2)
Pubmed 2 references available
Catalog no. ABIN655558
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 AA from the C-terminal region of human KILLIN.
Clone RB29503
Isotype Ig
Specificity This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the C-terminal region of human KILLIN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KILLIN
Background DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.
Synonyms: Killin
Molecular Weight 19958 DA
Gene ID 100144748
UniProt B2CW77, NP_001119521.1
Research Area Apoptosis/Necrosis, Cell Structure, Signaling, Transcription Factors
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Killin, p53-Regulated DNA Replication Inhibitor (KLLN) (C-Term), (AA 136-163) antibody KILLIN Antibody (C-term) (ABIN655558) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the KILLIN antibody detected the KILLIN protein (arrow).
Product cited in: Wang, Roma, Nolley et al.: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, 2014 (PubMed).

Background publications Cho, Liang: "Killin is a p53-regulated nuclear inhibitor of DNA synthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 14, pp. 5396-401, 2008 (PubMed).

Hosts (14)
Reactivities (14)
Applications (9), (5), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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