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Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 194-222), (Center) antibody

Details for Product No. ABIN655589, Supplier: Log in to see
Antigen
  • HEXIM1
  • fd44h02
  • hexim
  • wu:fd44h02
  • zgc:162976
  • CLP1
  • EDG1
  • HIS1
  • MAQ1
  • 7330426E13Rik
  • CLP-1
  • Clp1
  • Clp-1
Epitope
AA 194-222, Center
17
17
15
14
9
8
7
6
5
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
111
48
33
3
1
1
1
1
1
Host
Rabbit
85
16
15
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
5
5
5
4
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
97
64
37
22
14
11
9
4
3
2
1
Supplier
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Immunogen This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 AA from the Central region of human HEXIM1.
Clone RB29909
Isotype Ig
Specificity This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human HEXIM1.
Predicted Reactivity Cow (Bovine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HEXIM1 (HEXIM1 Antibody Abstract)
Background Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.
Synonyms: Protein HEXIM1,HEXIM1,CLP1, EDG1, HIS1, MAQ1
Molecular Weight 40623 DA
Gene ID 10614
NCBI Accession NP_006451
UniProt O94992
Research Area Cell Structure, Signaling, Protein Modifications, Phospho-specific antibodies, Transcription Factors, Translation Factors
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 194-222), (Center) antibody (ABIN655589) HEXIM1 antibody (Center) (ABIN655589) immunohistochemistry analysis in formalin fixed...
Background publications Ogba, Doughman, Chaplin et al.: "HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland." in: Oncogene, Vol. 29, Issue 25, pp. 3639-49, 2010 (PubMed).

Schönichen, Bigalke, Urbanke et al.: "A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1." in: Biochemistry, Vol. 49, Issue 14, pp. 3083-91, 2010 (PubMed).

Dow, Liu, Rice: "T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes." in: Journal of cellular physiology, Vol. 224, Issue 1, pp. 84-93, 2010 (PubMed).