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Details for Product No. ABIN655589

Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 194-222), (Center) antibody

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Antigen
Synonyms Clp1, HIS1, CLP-1, 7330426E13Rik, Clp-1, fd44h02, hexim, wu:fd44h02, zgc:162976, CLP1, EDG1, MAQ1, HEXIM1
Epitope
»Alternatives AA 194-222, Center
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN655589
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 AA from the Central region of human HEXIM1.
Clone RB29909
Isotype Ig
Specificity This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human HEXIM1.
Predicted Reactivity Cow (Bovine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HEXIM1
Background Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.
Synonyms: Protein HEXIM1,HEXIM1,CLP1, EDG1, HIS1, MAQ1
Molecular Weight 40623 DA
Gene ID 10614
UniProt O94992, NP_006451.1
Research Area Cell Structure, Signaling, Protein Modifications, Phospho-specific antibodies, Transcription Factors, Translation Factors
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Dow, Liu, Rice: "T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes." in: Journal of cellular physiology, Vol. 224, Issue 1, pp. 84-93, 2010 (PubMed).

Schönichen, Bigalke, Urbanke et al.: "A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1." in: Biochemistry, Vol. 49, Issue 14, pp. 3083-91, 2010 (PubMed).

Ogba, Doughman, Chaplin et al.: "HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland." in: Oncogene, Vol. 29, Issue 25, pp. 3639-49, 2010 (PubMed).

Alternatives for antigen "Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1)", type "Antibodies"
Hosts (34), (11), (6)
Reactivities (50), (31), (25), (1), (1), (1)
Applications (38), (26), (11), (10), (9), (6), (4), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (5), (5), (3), (2), (2), (2), (1), (1), (1)
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