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Details for Product No. ABIN655643

Slingshot Homolog 3 (Drosophila) (SSH3) (C-Term), (AA 575-602) antibody

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Antigen
Synonyms SSH3L, SSH-3, mSSH-3L, BC028922, SSH3
Epitope
»Alternatives C-Term, AA 575-602
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN655643
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 AA from the C-terminal region of human SSH3.
Clone RB19876
Isotype Ig
Specificity This SSH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 582-610 amino acids from the C-terminal region of human SSH3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SSH3
Background The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1, MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).
Synonyms: RB19876
Pathways: Regulation of actin cytoskeleton
Molecular Weight 72996 Da
Gene ID 54961
UniProt Q8TE77
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Kligys, Claiborne, DeBiase et al.: "The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32520-8, 2007 (PubMed).

Alternatives for antigen "Slingshot Homolog 3 (Drosophila) (SSH3)", type "Antibodies"
Hosts (19), (5)
Reactivities (24), (12), (11)
Applications (23), (15), (13), (6), (6), (5), (3), (2), (1)
Epitopes (7), (3), (2), (2), (2), (1), (1), (1)
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