Growth Arrest-Specific 1 (GAS1) (N-Term), (AA 95-127) antibody

Details for Product No. ABIN655812
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Antigen
Epitope
N-Term, AA 95-127
(6), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(30), (23), (11), (11), (11), (11), (11)
Host
Rabbit
(29), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
(21), (14), (9), (4), (2), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN655812
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Immunogen This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-127 AA from the N-terminal region of human GAS1.
Clone RB14523
Isotype Ig
Specificity This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the N-terminal region of human GAS1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GAS1
Background Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
Synonyms: Growth arrest-specific protein 1,GAS1,
Molecular Weight 35693 DA
Gene ID 2619
NCBI Accession NP_002039
UniProt P54826
Research Area Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Application Notes WB = 1:1000, IHC = 1:50-100, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Growth Arrest-Specific 1 (GAS1) (N-Term), (AA 95-127) antibody Confocal immunofluorescent analysis of GAS1 Antibody (N-term) (ABIN655812) with NCI-H460 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Background publications Zhao, Pan, Gang et al.: "Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26273-85, 2009 (PubMed).

Rittié, Stoll, Kang et al.: "Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin." in: Aging cell, Vol. 8, Issue 6, pp. 738-51, 2009 (PubMed).

Validation Images
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