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Details for Product No. ABIN655925

Eukaryotic Translation Initiation Factor 5A-Like 1 (EIF5AL1) (C-Term), (AA 94-122) antibody

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Antigen
Synonyms EIF5AP1, bA342M3.3
Epitope
»Alternatives C-Term, AA 94-122
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN655925
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 AA from the C-terminal region of human EIF5AL1.
Clone RB29799
Isotype Ig
Specificity This EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the C-terminal region of human EIF5AL1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EIF5AL1
Background EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).
Synonyms: EIF5AL1,Eukaryotic translation initiation factor 5A-1-like,
Molecular Weight 16773 DA
Gene ID 143244
UniProt NP_001093162.1, Q6IS14
Research Area Translation Factors, Signaling, Cell Structure, Protein Modifications, Chromatin
Application Notes Recommend dilutions: IHC : 1:10-50,WB : 1:1000,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.41 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Koettnitz, Wöhl, Kappel et al.: "Identification of a new member of the human eIF-5A gene family." in: Gene, Vol. 159, Issue 2, pp. 283-4, 1995 (PubMed).

Kim, Sprung, Chen et al.: "Substrate and functional diversity of lysine acetylation revealed by a proteomics survey." in: Molecular cell, Vol. 23, Issue 4, pp. 607-18, 2006 (PubMed).

Alternatives for antigen "Eukaryotic Translation Initiation Factor 5A-Like 1 (EIF5AL1)", type "Antibodies"
Hosts (3)
Reactivities (3)
Applications (3), (2), (2), (1), (1)
Epitopes (3), (2), (1)
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