V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) (C-Term), (AA 266-292) antibody

Details for Product No. ABIN656167
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Antigen
Synonyms MAFB, krml, Maf-B, XMafB, kreisler, MGC108453, valentino, KRML, MCTO, Krml, b-maf, kr, mafb, val, wu:fc22d11, wu:fj82a09, Kreisler, Krml1
Epitope
C-Term, AA 266-292
(8), (6), (2), (1), (1), (1)
Reactivity
Human
(21), (5), (3), (3), (3), (3), (2), (2)
Host
Rabbit
(19), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(22), (11), (6), (4), (4), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN656167
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Immunogen This MAFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 AA from the C-terminal region of human MAFB.
Clone RB31457
Isotype Ig
Specificity This MAFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MAFB.
Predicted Reactivity Mouse (Murine),Monkey,Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAFB
Background The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq].
Synonyms: MAFB,Transcription factor MafB,KRML
Molecular Weight 35792 DA
Gene ID 9935
NCBI Accession NP_005452
UniProt Q9Y5Q3
Research Area Ubiquitin-related antibodies, Translation Factors, Protein Modifications, Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MAFB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) (C-Term), (AA 266-292) antibody MAFB Antibody (C-term) (ABIN656167) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the MAFB antibody detected the MAFB protein (arrow).
Background publications Beaty, Murray, Marazita et al.: "A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4." in: Nature genetics, Vol. 42, Issue 6, pp. 525-9, 2010 (PubMed).

Kim, Seed: "The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3." in: Nature immunology, Vol. 11, Issue 8, pp. 743-50, 2010 (PubMed).

Validation Images
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