You are viewing an incomplete version of our website. Please click to reload the website as full version.

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 321-349), (Center) antibody

Details for Product No. ABIN656275, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms BL44, GCK, RAB8IP, AI385662, Rab8ip
AA 321-349, Center
(27), (21), (16), (15), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(54), (29), (9), (2), (2), (1), (1)
(69), (2)
Clonality (Clone)
Polyclonal ()
(6), (6), (6), (6), (6), (6)
Flow Cytometry (FACS), Western Blotting (WB)
(64), (50), (15), (13), (2), (2), (2), (2), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This MAP4K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-349 AA from the Central region of human MAP4K2.
Clone RB32275
Isotype Ig
Specificity This MAP4K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-349 amino acids from the Central region of human MAP4K2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAP4K2 (MAP4K2 Antibody Abstract)
Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Synonyms: MAP4K2,Mitogen-activated protein kinase kinase kinase kinase 2,GCK, RAB8IP
Molecular Weight 91556 DA
Gene ID 5871
NCBI Accession NP_004570
UniProt Q12851
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Chromatin, Signaling
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MAP4K2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 321-349), (Center) antibody (ABIN656275) MAP4K2 Antibody (Center) (ABIN656275) western blot analysis in Jurkat cell line lysat...
Background publications Fidalgo, Fraile, Pires et al.: "CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation." in: Journal of cell science, Vol. 123, Issue Pt 8, pp. 1274-84, 2010 (PubMed).

Chadee, Yuasa, Kyriakis: "Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2." in: Molecular and cellular biology, Vol. 22, Issue 3, pp. 737-49, 2002 (PubMed).

Catalog No. ABIN656275
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)