UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) (AA 156-185), (Center) antibody

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Antigen
Epitope
AA 156-185, Center
(8), (6), (4), (3), (1)
Reactivity
Human
(16)
Host
Rabbit
(15), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
(16), (7), (7), (7), (6), (3), (2), (2), (2)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN656309
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Immunogen This UGT2B15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 AA from the Central region of human UGT2B15.
Clone RB31273
Isotype Ig
Specificity This UGT2B15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the Central region of human UGT2B15.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UGT2B15
Background The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).
Synonyms: UGT2B15,UDP-glucuronosyltransferase 2B15,UGT2B8
Molecular Weight 60988 DA
Gene ID 7366
NCBI Accession NP_001067
UniProt P54855
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment UGT2B15 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) (AA 156-185), (Center) antibody UGT2B15 Antibody (Center) western blot analysis in NCI-H460(lane 1),HepG2(lane 2),ZR-75-1(lane 3) cell line lysates (35ug/lane).This demonstrates the UGT2B15 antibody detected the UGT2B15 protein (arrow).
anti-UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) (AA 156-185), (Center) antibody (2) UGT2B15 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT2B15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) (AA 156-185), (Center) antibody (3) Confocal immunofluorescent analysis of UGT2B15 Antibody (Center) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
anti-UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) (AA 156-185), (Center) antibody (4) UGT2B15 Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Holmes, Shah, Vickery et al.: "Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies." in: PLoS ONE, Vol. 4, Issue 12, pp. e7960, 2009 (PubMed).

Yong, Schwartz, Atkinson et al.: "Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 2, pp. 537-46, 2010 (PubMed).

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