CCT8 antibody (C-Term)

Catalog No. ABIN656431

Product Details anti-CCT8 Antibody

Target: CCT8 (Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8))

Binding Specificity: AA 519-548, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human CCT8.

Clone: RB31130

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CCT8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-CCT8 antibody (ABIN656431)

Yin, Miao, Wu, Wei, Zong, Yang, Chen, Zheng, Zhu, Guo, Li, Chen, Wang, He: "The role of the Chaperonin containing t-complex polypeptide 1, subunit 8 (CCT8) in B-cell non-Hodgkin's lymphoma." in: Leukemia research, Vol. 45, pp. 59-67, (2017) (PubMed).

Qiu, He, Huang, Liu, Sun, Guo, Yuan, Yang, Ban, Fan, Tao, Wang: "Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in glioma." in: Pathology, research and practice, Vol. 211, Issue 10, pp. 717-25, (2016) (PubMed).

Target Details for CCT8

Target: CCT8 (Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8))

Alternative Name: CCT8 (CCT8 Products)

Background: Molecular chaperone, CCT8 assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Molecular Weight: 59621

Gene ID: 10694

NCBI Accession: NP_006576

UniProt: P50990