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Sterol Carrier Protein 2 (SCP2) (AA 14-43), (N-Term) antibody

Details for Product No. ABIN656448, Supplier: Login to see
Antigen
  • AI586070
  • D10Ertd73e
  • OS-4
  • OS4
  • SCP2
  • PLTP
  • NLTP
  • NSL-TP
  • SCP-2
  • SCP-CHI
  • SCP-X
  • SCPX
  • NSLIPTR
  • SCPx
  • AA409774
  • AA409893
  • C76618
  • C79031
  • ns-LTP
Epitope
AA 14-43, N-Term
31
19
16
11
4
3
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
122
27
25
4
3
3
2
1
1
Host
Rabbit
88
19
15
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
9
9
9
5
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
66
47
15
11
4
3
3
Supplier
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Immunogen This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 AA from the N-terminal region of human SCP2.
Clone RB31279
Isotype Ig
Specificity This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of human SCP2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SCP2 (SCP2 Antibody Abstract)
Background This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Synonyms: Non-specific lipid-transfer protein,SCP2,
Molecular Weight 58994 DA
Gene ID 6342
NCBI Accession NP_002970, NP_001007251, NP_001007101, NP_001007100
UniProt P22307
Research Area Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SCP2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sterol Carrier Protein 2 (SCP2) (AA 14-43), (N-Term) antibody (ABIN656448) SCP2 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).T...
Immunohistochemistry (IHC) image for anti-Sterol Carrier Protein 2 (SCP2) (AA 14-43), (N-Term) antibody (ABIN656448) SCP2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Background publications Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).