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Regulatory Factor X 3 (RFX3) (AA 661-690), (C-Term) antibody

Details for Product No. ABIN656557, Supplier: Login to see
Antigen
  • ba32f11.1
  • C230093O12Rik
  • MRFX3
  • zgc:153245
Epitope
AA 661-690, C-Term
24
16
2
2
1
1
1
1
1
Reactivity
Human
46
12
7
2
Host
Rabbit
42
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
39
25
8
3
2
1
Supplier
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Immunogen This RFX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-690 AA from the C-terminal region of human RFX3.
Clone RB32572
Isotype Ig
Specificity This RFX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-690 amino acids from the C-terminal region of human RFX3.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RFX3 (RFX3 Antibody Abstract)
Background This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
Synonyms: Transcription factor RFX3,RFX3,
Molecular Weight 83530 DA
Gene ID 5991
NCBI Accession NP_002910, NP_602304
UniProt P48380
Research Area Translation Factors, Cell Cycle, Transcription Factors, Signaling, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.31 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment RFX3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Regulatory Factor X 3 (RFX3) (AA 661-690), (C-Term) antibody (ABIN656557) RFX3 Antibody (C-term) (ABIN656557) western blot analysis in MDA-MB435 cell line lysa...
Background publications El Zein, Ait-Lounis, Morlé et al.: "RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies." in: Journal of cell science, Vol. 122, Issue Pt 17, pp. 3180-9, 2009 (PubMed).

Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).

Morotomi-Yano, Yano, Saito et al.: "Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 836-42, 2002 (PubMed).