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IRF4 antibody (Interferon Regulatory Factor 4) (AA 164-191)

Details for Product anti-IRF4 Antibody No. ABIN656568, Supplier: Login to see New
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Synonyms IRF4, irf4, LSIRF, MUM1, NF-EM5, AI385587, IRF-4, Spip, si:ch73-170d1.2
AA 164-191, Center
(32), (8), (8), (7), (6), (6), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(145), (48), (19), (3), (2), (2), (2), (2), (1)
(96), (24), (15), (13), (2)
Clonality (Clone)
Polyclonal ()
This IRF4 antibody is un-conjugated
(4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Flow Cytometry (FACS), Western Blotting (WB)
(119), (53), (36), (30), (21), (12), (8), (5), (5), (5), (4), (3), (1)
Pubmed 3 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 AA from the Central region of human IRF4.
Clone RB17417
Isotype Ig
Specificity This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name IRF4 (IRF4 Antibody Abstract)
Background The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Synonyms: Interferon regulatory factor 4,IRF4,MUM1
Molecular Weight 51772 DA
Gene ID 3662
NCBI Accession NP_002451, NP_001182215
UniProt Q15306
Research Area Translation Factors, Transcription Factors, Chromatin, Signaling, Cell Structure
Pathways TCR Signaling
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment IRF4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-IRF4 antibody (Interferon Regulatory Factor 4) (AA 164-191) (ABIN656568) Western blot analysis of IRF4 (arrow) using rabbit polyclonal IRF4 Antibody (Center) ...
Background publications Staudt, Bothur, Klein et al.: "Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells." in: Immunity, Vol. 33, Issue 2, pp. 192-202, 2010 (PubMed).

Newton-Bishop, Chang, Iles et al.: "Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 8, pp. 2043-54, 2010 (PubMed).

Ucisik-Akkaya, Davis, Do et al.: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, 2010 (PubMed).

Catalog No. ABIN656568
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