Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN656726

Chromosome 10 Open Reading Frame 2 (C1ORF2) (C-Term), (AA 656-684) antibody

Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms ATXN8, IOSCA, MTDPS7, PEO, PEO1, PEOA3, SANDO, SCA8, TWINL, D19Ertd626e, Twinl, C6H10orf2
»Alternatives C-Term, AA 656-684
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN656726
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-684 AA from the C-terminal region of human C10orf2.
Clone RB32016
Isotype Ig
Specificity This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-684 amino acids from the C-terminal region of human C10orf2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name C10orf2
Background This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Synonyms: Twinkle protein, mitochondrial,PEO1,C10orf2
Molecular Weight 77154 DA
Gene ID 56652
UniProt NP_001157284.1, NP_068602.2, Q96RR1
Research Area Cell Signaling, Chromatin, Signaling, Metabolism, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment C10orf2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Longley, Humble, Sharief et al.: "Disease variants of the human mitochondrial DNA helicase encoded by C10orf2 differentially alter protein stability, nucleotide hydrolysis, and helicase activity." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29690-702, 2010 (PubMed).

Alternatives for antigen "Chromosome 10 Open Reading Frame 2 (C1ORF2)", type "Antibodies"
Hosts (8), (1)
Reactivities (7), (2), (2), (2), (1), (1), (1)
Applications (9), (3), (2), (1)
Epitopes (2), (2), (2), (1), (1), (1)