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Details for Product No. ABIN656747

DSN1, MIND Kinetochore Complex Component, Homolog (S. Cerevisiae) (DSN1) (C-Term), (AA 257-286) antibody

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Antigen
Synonyms C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3, 1700022L09Rik, AW552447
Epitope
»Alternatives C-Term, AA 257-286
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN656747
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 AA from the C-terminal region of human DSN1.
Clone RB32490
Isotype Ig
Specificity This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-295 amino acids from the C-terminal region of human DSN1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DSN1
Background This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.
Synonyms: Kinetochore-associated protein DSN1 homolog,DSN1,C20orf172, MIS13
Molecular Weight 40067 DA
Gene ID 79980
UniProt Q9H410, NP_001138787.1, NP_079194.3, NP_001138788.1
Research Area Phospho-specific antibodies, Protein Modifications, Cell Cycle, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DSN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Kiyomitsu, Obuse, Yanagida: "Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1." in: Developmental cell, Vol. 13, Issue 5, pp. 663-76, 2007 (PubMed).

Cheeseman, Desai: "Molecular architecture of the kinetochore-microtubule interface." in: Nature reviews. Molecular cell biology, Vol. 9, Issue 1, pp. 33-46, 2007 (PubMed).

Yang, Wu, Ward et al.: "Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore." in: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26726-36, 2008 (PubMed).

Alternatives for antigen "DSN1, MIND Kinetochore Complex Component, Homolog (S. Cerevisiae) (DSN1)", type "Antibodies"
Hosts (21), (1)
Reactivities (22), (11), (11), (11), (11)
Applications (12), (9), (5), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (1), (1), (1)
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