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HIST1H2BC,HIST1H2BF (AA 1-30), (N-Term) antibody

Details for Product No. ABIN656773, Supplier: Log in to see
Antigen
Epitope
AA 1-30, N-Term
3
1
Reactivity
Human
3
Host
Rabbit
3
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
2
Options
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Immunogen This HIST1H2BC/HIST1H2BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human HIST1H2BC/HIST1H2BF.
Clone RB32591
Isotype Ig
Specificity This HIST1H2BC/HIST1H2BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BC/HIST1H2BF.
Predicted Reactivity Cow (Bovine),Chicken,Mouse (Murine),Monkey,Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HIST1H2BC/HIST1H2BF
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H2B type 1-C/E/F/G/I,HIST1H2BC,H2BFL
Molecular Weight 13906 DA
Gene ID 8347
NCBI Accession NP_003509, NP_003514, NP_003513, NP_003516, NP_003517
UniProt P62807
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment HIST1H2BC/HIST1H2BF Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.Precau.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-HIST1H2BC,HIST1H2BF (AA 1-30), (N-Term) antibody (ABIN656773) HIST1H2BC/HIST1H2BF Antibody (N-term) (ABIN656773) western blot analysis in MDA-MB435...
Background publications Kim, Sprung, Chen, Xu, Ball, Pei, Cheng, Kho, Xiao, Xiao, Grishin, White, Yang, Zhao: "Substrate and functional diversity of lysine acetylation revealed by a proteomics survey." in: Molecular cell, Vol. 23, Issue 4, pp. 607-18, 2006 (PubMed).