Taste Receptor, Type 2, Member 1 (TAS2R1) (C-Term), (AA 267-296) antibody

Details for Product No. ABIN656905
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Antigen
Epitope
C-Term, AA 267-296
(8), (7), (6), (1), (1), (1), (1)
Reactivity
Human
(24)
Host
Rabbit
(24)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (20), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN656905
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Immunogen This TAS2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 AA from the C-terminal region of human TAS2R1.
Clone RB32501
Isotype Ig
Specificity This TAS2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-297 amino acids from the C-terminal region of human TAS2R1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TAS2R1
Background This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil.
Synonyms: Taste receptor type 2 member 1,TAS2R1,
Molecular Weight 34333 DA
Gene ID 50834
NCBI Accession NP_062545
UniProt Q9NYW7
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment TAS2R1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Taste Receptor, Type 2, Member 1 (TAS2R1) (C-Term), (AA 267-296) antibody TAS2R1 Antibody (C-term) (ABIN656905) western blot analysis in MDA-MB231,293,NCI-H292 cell line lysates (35 µg/lane). This demonstrates the TAS2R1 antibody detected the TAS2R1 protein (arrow).
Background publications Weiss, Arking, et al.: "A genome-wide linkage and association scan reveals novel loci for autism." in: Nature, Vol. 461, Issue 7265, pp. 802-8, 2009 (PubMed).

Upadhyaya, Pydi, Singh et al.: "Bitter taste receptor T2R1 is activated by dipeptides and tripeptides." in: Biochemical and biophysical research communications, Vol. 398, Issue 2, pp. 331-5, 2010 (PubMed).

Validation Images
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