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Details for Product No. ABIN657026

RAS, Dexamethasone-Induced 1 (RASD1) (C-Term), (AA 248-277) antibody

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Antigen
Synonyms AGS1, DEXRAS1, MGC:26290, Dexras1
Epitope
»Alternatives C-Term, AA 248-277
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN657026
Quantity 400 ┬ÁL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 AA from the C-terminal region of human RASD1.
Clone RB31294
Isotype Ig
Specificity This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-278 amino acids from the C-terminal region of human RASD1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASD1
Background This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.
Synonyms: Dexamethasone-induced Ras-related protein 1,RASD1,AGS1, DEXRAS1
Research Area Signaling, Protein Modifications, Cell Structure, Chromatin
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Lau, Chan, Perkinton et al.: "Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34728-37, 2008 (PubMed).

Nojima, Maruyama, Yasui et al.: "Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4356-64, 2009 (PubMed).

Alternatives for antigen "RAS, Dexamethasone-Induced 1 (RASD1)", type "Antibodies"
Hosts (3), (1)
Reactivities (3), (2)
Applications (3), (2), (1), (1), (1)
Epitopes (3), (1), (1), (1)
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