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Details for Product No. ABIN657236

WD Repeat Domain 45 (WDR45) (N-Term), (AA 17-46) antibody

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Antigen
Synonyms NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4, JM5, Sfc19, Wdrx1, C79260, DXImx38e, zgc:56345, zgc:77017, MGC80694
Epitope
»Alternatives N-Term, AA 17-46
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN657236
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 AA from the N-terminal region of human WDR45.
Clone RB33311
Isotype Ig
Specificity This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human WDR45.
Predicted Reactivity Mouse (Murine),Rat (Rattus),Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name WDR45
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
Synonyms: WD repeat domain phosphoinositide-interacting protein 4,WDR45,WDRX1, WDRXI4, WIPI4
Research Area Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Clark, Glanowski, Nielsen et al.: "Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios." in: Science (New York, N.Y.), Vol. 302, Issue 5652, pp. 1960-3, 2003 (PubMed).

Jeffries, Dove, Michell et al.: "PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2652-63, 2004 (PubMed).

Proikas-Cezanne, Waddell, Gaugel et al.: "WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy." in: Oncogene, Vol. 23, Issue 58, pp. 9314-25, 2004 (PubMed).

Alternatives for antigen "WD Repeat Domain 45 (WDR45)", type "Antibodies"
Hosts (5), (1)
Reactivities (5), (2), (2)
Applications (3), (2), (2), (1), (1)
Epitopes (2), (1), (1), (1)
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