WD Repeat Domain 45 (WDR45) (N-Term), (AA 17-46) antibody

Details for Product No. ABIN657236
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Antigen
Synonyms MGC80694, NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4, C79260, DXImx38e, JM5, Sfc19, Wdrx1, zgc:56345, zgc:77017
Epitope
N-Term, AA 17-46
(7), (7), (1), (1), (1)
Reactivity
Human
(14), (2), (2)
Host
Rabbit
(13), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(10), (10), (4), (1), (1)
Pubmed 3 references available
Quantity 400 μL
Options
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Catalog No. ABIN657236
291.50 $
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Immunogen This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 AA from the N-terminal region of human WDR45.
Clone RB33311
Isotype Ig
Specificity This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human WDR45.
Predicted Reactivity Mouse (Murine),Rat (Rattus),Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name WDR45
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
Synonyms: WD repeat domain phosphoinositide-interacting protein 4,WDR45,WDRX1, WDRXI4, WIPI4
Research Area Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-WD Repeat Domain 45 (WDR45) (N-Term), (AA 17-46) antibody WDR45 Antibody (N-term) (ABIN657236) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the WDR45 antibody detected the WDR45 protein (arrow).
Background publications Clark, Glanowski, Nielsen et al.: "Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios." in: Science (New York, N.Y.), Vol. 302, Issue 5652, pp. 1960-3, 2003 (PubMed).

Jeffries, Dove, Michell et al.: "PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2652-63, 2004 (PubMed).

Proikas-Cezanne, Waddell, Gaugel et al.: "WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy." in: Oncogene, Vol. 23, Issue 58, pp. 9314-25, 2004 (PubMed).

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