Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) (N-Term), (AA 69-98) antibody

Details for Product No. ABIN657279
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Antigen
Synonyms drapc1, xPgo, APCDD1, Pgo1, cAPCDD1, B7323, DRAPC1, HHS, HTS, AB023957, AU041258, Drapc1, EIG180
Epitope
N-Term, AA 69-98
(6), (6), (5), (1), (1), (1), (1)
Reactivity
Human
(32), (19), (19), (12), (12), (7)
Host
Rabbit
(31), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(23), (10), (10), (9), (4), (1)
Pubmed 2 references available
Quantity 400 μL
Options
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Catalog No. ABIN657279
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Immunogen This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 AA from the N-terminal region of human APCDD1.
Clone RB33555
Isotype Ig
Specificity This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the N-terminal region of human APCDD1.
Predicted Reactivity Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name APCDD1
Background This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.
Synonyms: Protein APCDD1,APCDD1,DRAPC1
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) (N-Term), (AA 69-98) antibody APCDD1 Antibody (N-term) (ABIN657279) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the APCDD1 antibody detected the APCDD1 protein (arrow).
Background publications Takahashi, Fujita, Furukawa et al.: "Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis." in: Cancer research, Vol. 62, Issue 20, pp. 5651-6, 2002 (PubMed).

Shimomura, Agalliu, Vonica et al.: "APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex." in: Nature, Vol. 464, Issue 7291, pp. 1043-7, 2010 (PubMed).

Validation Images
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