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Details for Product No. ABIN657279

Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1) (N-Term), (AA 69-98) antibody

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Antigen
Synonyms B7323, DRAPC1, HHS, HTS, Pgo1, cAPCDD1, Drapc1, EIG180, AB023957, AU041258, drapc1, xPgo, APCDD1
Epitope
»Alternatives N-Term, AA 69-98
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN657279
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 AA from the N-terminal region of human APCDD1.
Clone RB33555
Isotype Ig
Specificity This APCDD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the N-terminal region of human APCDD1.
Predicted Reactivity Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name APCDD1
Background This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.
Synonyms: Protein APCDD1,APCDD1,DRAPC1
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Takahashi, Fujita, Furukawa et al.: "Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis." in: Cancer research, Vol. 62, Issue 20, pp. 5651-6, 2002 (PubMed).

Shimomura, Agalliu, Vonica et al.: "APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex." in: Nature, Vol. 464, Issue 7291, pp. 1043-7, 2010 (PubMed).

Alternatives for antigen "Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1)", type "Antibodies"
Hosts (28), (1)
Reactivities (26), (24), (21), (12), (12), (7), (2)
Applications (20), (10), (5), (4), (4), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (2), (1), (1), (1), (1), (1)
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