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Dynactin 4 (DCTN4) (AA 1-30), (N-Term) antibody

Details for Product No. ABIN657377, Supplier: Login to see
Antigen
  • 1110001K06Rik
  • 4930547K17Rik
  • C130039E17Rik
  • p62
  • DYN4
  • P62
Epitope
AA 1-30, N-Term
18
16
8
2
Reactivity
Human
47
15
11
Host
Rabbit
34
14
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
28
22
9
8
3
3
2
2
Supplier
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Immunogen This DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human DCTN4.
Clone RB32888
Isotype Ig
Specificity This DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCTN4.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DCTN4 (DCTN4 Antibody Abstract)
Background DCTN4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Synonyms: Dynactin subunit 4,DCTN4,
Molecular Weight 52337 DA
Gene ID 51164
NCBI Accession NP_057305
UniProt Q9UJW0
Research Area Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment DCTN4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Dynactin 4 (DCTN4) (AA 1-30), (N-Term) antibody (ABIN657377) DCTN4 Antibody (N-term) (ABIN657377) western blot analysis in ZR-75-1 cell line lysat...
Background publications Ayalon, Davis, Scotland et al.: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, 2008 (PubMed).

Boultwood, Fidler, Strickson et al.: "Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs." in: Genomics, Vol. 66, Issue 1, pp. 26-34, 2000 (PubMed).

Karki, Tokito, Holzbaur: "A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1." in: The Journal of biological chemistry, Vol. 275, Issue 7, pp. 4834-9, 2000 (PubMed).