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Details for Product No. ABIN657377

Dynactin 4 (DCTN4) (N-Term), (AA 1-30) antibody

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Antigen
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN657377
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human DCTN4.
Clone RB32888
Isotype Ig
Specificity This DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCTN4.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DCTN4
Background DCTN4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Synonyms: Dynactin subunit 4,DCTN4,
Molecular Weight 52337 DA
Gene ID 51164
UniProt NP_057305.1, Q9UJW0
Research Area Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DCTN4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Karki, Tokito, Holzbaur: "A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1." in: The Journal of biological chemistry, Vol. 275, Issue 7, pp. 4834-9, 2000 (PubMed).

Boultwood, Fidler, Strickson et al.: "Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs." in: Genomics, Vol. 66, Issue 1, pp. 26-34, 2000 (PubMed).

Ayalon, Davis, Scotland et al.: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, 2008 (PubMed).

Alternatives for antigen "Dynactin 4 (DCTN4)", type "Antibodies"
Hosts (10), (8)
Reactivities (16), (7), (3)
Applications (15), (7), (6), (4), (3), (2), (2), (2)
Epitopes (4), (2), (2), (2)
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