Midline 1 (MID1) (C-Term), (AA 575-603) antibody

Details for Product No. ABIN657388
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Antigen
Synonyms 61B3-R, DXHXS1141, Fxy, Trim18, bbbg1, fxy, gbbb1, midin, ogs1, osx, rnf59, trim18, xprf, znfxy, BBBG1, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY, Midline1
Epitope
C-Term, AA 575-603
(9), (7), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(34), (14), (14), (13), (13), (12), (1), (1), (1)
Host
Rabbit
(30), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (13), (10), (4), (2), (2)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN657388
291.50 $
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Immunogen This MID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 AA from the C-terminal region of human MID1.
Clone RB33237
Isotype Ig
Specificity This MID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-603 amino acids from the C-terminal region of human MID1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MID1
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing, however, the full-length nature of some of the variants has not been determined.
Synonyms: Midline-1,MID1,FXY, RNF59, TRIM18, XPRF
Molecular Weight 75251 DA
Gene ID 4281
NCBI Accession NP_001180206, NP_000372, NP_001180207, NP_001092094
UniProt O15344
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MID1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Midline 1 (MID1) (C-Term), (AA 575-603) antibody MID1 Antibody (C-term) (ABIN657388) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the MID1 antibody detected the MID1 protein (arrow).
Background publications Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Validation Images
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