Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (C-Term), (AA 357-386) antibody

Details for Product No. ABIN657393
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Antigen
Epitope
C-Term, AA 357-386
(31), (11), (7), (7), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(91), (44), (32), (16), (15), (12), (12), (1), (1)
Host
Rabbit
(86), (6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(80), (48), (42), (16), (10), (5), (4), (4), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN657393
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Immunogen This GOPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-386 AA from the C-terminal region of human GOPC.
Clone RB33292
Isotype Ig
Specificity This GOPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-378 amino acids from the C-terminal region of human GOPC.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GOPC
Background PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].
Synonyms: Golgi-associated PDZ and coiled-coil motif-containing protein,GOPC,CAL, FIG
Molecular Weight 50520 DA
Gene ID 57120
NCBI Accession NP_065132, NP_001017408
UniProt Q9HD26
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Chromatin, Signaling, Neurology
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.31 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment GOPC Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (C-Term), (AA 357-386) antibody Western blot analysis of GOPC (arrow) using rabbit polyclonal GOPC Antibody (C-term) (ABIN657393). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GOPC gene.
Background publications Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Cushing, Fellows, Villone et al.: "The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling." in: Biochemistry, Vol. 47, Issue 38, pp. 10084-98, 2008 (PubMed).

Cheng, Cebotaru, Cebotaru et al.: "Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator." in: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1178-87, 2010 (PubMed).

Validation Images
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