Butyrophilin, Subfamily 3, Member A1 (BTN3A1) (C-Term), (AA 345-374) antibody

Details for Product No. ABIN657422
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Antigen
Synonyms BT3.1, BTF5, CD277, BTN3A1
Epitope
C-Term, AA 345-374
(8), (7), (1)
Reactivity
Human
(13)
Host
Rabbit
(9), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(9), (6), (4), (3)
Pubmed 5 references available
Quantity 400 μL
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Catalog No. ABIN657422
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Immunogen This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 AA from the C-terminal region of human BTN3A1.
Clone RB33424
Isotype Ig
Specificity This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-374 amino acids from the C-terminal region of human BTN3A1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BTN3A1
Background The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1, MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM].
Synonyms: Butyrophilin subfamily 3 member A1,BTN3A1,BTF5
Molecular Weight 57677 DA
Gene ID 11119
NCBI Accession NP_919423, NP_001138480, NP_001138481, NP_008979
UniProt O00481
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment BTN3A1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Butyrophilin, Subfamily 3, Member A1 (BTN3A1) (C-Term), (AA 345-374) antibody BTN3A1 Antibody (C-term) (ABIN657422) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the BTN3A1 antibody detected the BTN3A1 protein (arrow).
Background publications Rhodes, Stammers, Malcherek et al.: "The cluster of BTN genes in the extended major histocompatibility complex." in: Genomics, Vol. 71, Issue 3, pp. 351-62, 2001 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Wang, Yoon, Oh et al.: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006 (PubMed).

Shi, Levinson, Duan et al.: "Common variants on chromosome 6p22.1 are associated with schizophrenia." in: Nature, Vol. 460, Issue 7256, pp. 753-7, 2009 (PubMed).

Smith, Knezevic, Ammann et al.: "BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3514-25, 2010 (PubMed).

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