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BTN3A1 antibody (Butyrophilin, Subfamily 3, Member A1) (AA 345-374)

Details for Product anti-BTN3A1 Antibody No. ABIN657422, Supplier: Log in to see
Antigen
  • BT3.1
  • BTF5
  • BTN3A1
  • CD277
Epitope
AA 345-374, C-Term
17
14
1
Reactivity
Human
24
Host
Rabbit
18
6
Clonality (Clone)
Polyclonal ()
Conjugate
This BTN3A1 antibody is un-conjugated
4
2
2
2
2
2
Application
Western Blotting (WB)
19
13
4
2
2
Supplier
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Immunogen This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 AA from the C-terminal region of human BTN3A1.
Clone RB33424
Isotype Ig
Specificity This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-374 amino acids from the C-terminal region of human BTN3A1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BTN3A1 (BTN3A1 Antibody Abstract)
Background The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1, MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM].
Synonyms: Butyrophilin subfamily 3 member A1,BTN3A1,BTF5
Molecular Weight 57677 DA
Gene ID 11119
NCBI Accession NP_919423, NP_001138480, NP_001138481, NP_008979
UniProt O00481
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment BTN3A1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-BTN3A1 antibody (Butyrophilin, Subfamily 3, Member A1) (AA 345-374) (ABIN657422) BTN3A1 Antibody (C-term) (ABIN657422) western blot analysis in MDA-MB231 cell line ly...
Background publications Smith, Knezevic, Ammann, Rhodes, Aw, Palmer, Mather, Trowsdale: "BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3514-25, 2010

Shi, Levinson, Duan, Sanders, Zheng, Peer, Dudbridge, Holmans, Whittemore, Mowry, Olincy, Amin, Cloninger, Silverman, Buccola, Byerley, Black, Crowe, Oksenberg, Mirel, Kendler, Freedman, Gejman: "Common variants on chromosome 6p22.1 are associated with schizophrenia." in: Nature, Vol. 460, Issue 7256, pp. 753-7, 2009

Wang, Yoon, Oh, Jeon, Kim, Kim, Byun, Yang, Kim, Kim, Yeom, Yoo, Kim, Kim: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003

Rhodes, Stammers, Malcherek, Beck, Trowsdale: "The cluster of BTN genes in the extended major histocompatibility complex." in: Genomics, Vol. 71, Issue 3, pp. 351-62, 2001