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Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1) (AA 207-236), (C-Term) antibody

Details for Product No. ABIN657579, Supplier: Login to see
Antigen
  • zgc:101585
  • lsfr2
  • DOLPP1
  • 0610011H20Rik
  • AB030189
  • LSFR2
Epitope
AA 207-236, C-Term
15
15
4
1
Reactivity
Mouse (Murine)
19
7
4
1
1
1
1
Host
Rabbit
22
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
20
15
Supplier
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Immunogen This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 AA from the C-terminal region of human DOLPP1.
Clone RB33347
Isotype Ig
Specificity This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human DOLPP1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DOLPP1 (DOLPP1 Antibody Abstract)
Background DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).
Synonyms: Dolichyldiphosphatase 1,DOLPP1,
Molecular Weight 27031 DA
Gene ID 57171
NCBI Accession NP_065171, NP_001129389
UniProt Q86YN1
Research Area Cell Structure, Metabolism
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment DOLPP1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1) (AA 207-236), (C-Term) antibody (ABIN657579) DOLPP1 Antibody (C-term) (ABIN657579) western blot analysis in mouse stomach tissue l...
Background publications Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).

Rush, Cho, Jiang et al.: "Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45226-34, 2002 (PubMed).

Gilley, Fried: "Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes." in: Human molecular genetics, Vol. 8, Issue 7, pp. 1313-20, 1999 (PubMed).

Wedgwood, Strominger: "Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate." in: The Journal of biological chemistry, Vol. 255, Issue 3, pp. 1120-3, 1980 (PubMed).