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Details for Product No. ABIN657653

H1 Histone Family, Member X (H1FX) (C-Term), (AA 138-167) antibody

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Antigen
Synonyms H1X, Gm461, cb1061, wu:fb12d01, wu:fb63d02, h1x, MGC53643, MGC130834, RGD1565596
Epitope
»Alternatives C-Term, AA 138-167
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN657653
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This H1FX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 AA from the C-terminal region of human H1FX.
Clone RB33707
Isotype Ig
Specificity This H1FX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-167 amino acids from the C-terminal region of human H1FX.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name H1FX
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.
Synonyms: Histone H1x,H1FX,
Molecular Weight 22487 DA
Gene ID 8971
UniProt Q92522, NP_006017.1
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment H1FX Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Takata, Matsunaga, Morimoto et al.: "H1.X with different properties from other linker histones is required for mitotic progression." in: FEBS letters, Vol. 581, Issue 20, pp. 3783-8, 2007 (PubMed).

Stoldt, Wenzel, Schulze et al.: "G1 phase-dependent nucleolar accumulation of human histone H1x." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 99, Issue 10, pp. 541-52, 2007 (PubMed).

Warneboldt, Haller, Horstmann et al.: "Histone H1x is highly expressed in human neuroendocrine cells and tumours." in: BMC cancer, Vol. 8, pp. 388, 2009 (PubMed).

Alternatives for antigen "H1 Histone Family, Member X (H1FX)", type "Antibodies"
Hosts (2), (2)
Reactivities (4)
Applications (4), (2), (1), (1)
Epitopes (2), (1), (1), (1)
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