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Details for Product No. ABIN657694

Napsin A Aspartic Peptidase (NAPSA) (C-Term), (AA 368-397) antibody

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Antigen
Synonyms KAP, Kdap, NAP1, NAPA, SNAPA, pronapsin
Epitope
»Alternatives C-Term, AA 368-397
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN657694
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This NAPSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-397 AA from the C-terminal region of human NAPSA.
Clone RB33879
Isotype Ig
Specificity This NAPSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-397 amino acids from the C-terminal region of human NAPSA.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NAPSA
Background The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq].
Synonyms: Napsin-A,NAPSA,NAP1, NAPA
Molecular Weight 45387 DA
Gene ID 9476
UniProt O96009, NP_004842.1
Research Area Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment NAPSA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Brasch, Ochs, Kahne et al.: "Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung." in: The Journal of biological chemistry, Vol. 278, Issue 49, pp. 49006-14, 2003 (PubMed).

Innocenti, Zucconi, Disanza et al.: "Abi1 is essential for the formation and activation of a WAVE2 signalling complex." in: Nature cell biology, Vol. 6, Issue 4, pp. 319-27, 2004 (PubMed).

Bishop, Sharma, Illei: "Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma." in: Human pathology, Vol. 41, Issue 1, pp. 20-5, 2009 (PubMed).

Alternatives for antigen "Napsin A Aspartic Peptidase (NAPSA)", type "Antibodies"
Hosts (28), (16), (3)
Reactivities (47), (15), (14), (12), (12), (1), (1), (1)
Applications (24), (14), (10), (9), (5), (5), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (1), (1), (1), (1), (1), (1)
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