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RANGAP1 antibody (N-Term)

RANGAP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33892 unconjugated
Catalog No. ABIN657698
  • Target See all RANGAP1 Antibodies
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    Binding Specificity
    • 12
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 20-49, N-Term
    Reactivity
    • 53
    • 26
    • 25
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 41
    • 12
    Polyclonal
    Conjugate
    • 29
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RANGAP1 antibody is un-conjugated
    Application
    • 35
    • 25
    • 19
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.
    Clone
    RB33892
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RANGAP1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    Alternative Name
    RANGAP1 (RANGAP1 Products)
    Synonyms
    Fug1 antibody, RANGAP antibody, SD antibody, ATRANGAP1 antibody, RAN GTPASE-ACTIVATING PROTEIN 1 antibody, RAN GTPase activating protein 1 antibody, RanGAP1 antibody, fug1 antibody, rangap1b antibody, rna1p antibody, C79654 antibody, mKIAA1835 antibody, rangap1 antibody, rangap1a antibody, Protein rna1 antibody, CG9999 antibody, CT28175 antibody, Dmel\CG9999 antibody, RGP1_DROME antibody, Ran antibody, RanGAP antibody, RanGap antibody, RanGap1 antibody, Scl antibody, Sd antibody, Sd-RanGAP antibody, Sd-RanGap antibody, dRanGAP antibody, ranGAP antibody, ranGap antibody, rangap antibody, zgc:154097 antibody, Ran GTPase activating protein 1 antibody, RAN GTPase activating protein 1 antibody, ran GTPase activating protein 1 antibody, Ran GTPase activating protein 1 S homeolog antibody, Ran GTPase activating protein 1 L homeolog antibody, Ran GAP Rna1 antibody, Ran GTPase activating protein antibody, RAN GTPase activating protein 1a antibody, RANGAP1 antibody, TERG_02084 antibody, rangap1.S antibody, Rangap1 antibody, rangap1.L antibody, rna1 antibody, RanGAP antibody, rangap1a antibody
    Background
    RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
    Molecular Weight
    63542
    Gene ID
    5905
    NCBI Accession
    NP_001265580, NP_002874
    UniProt
    P46060
    Pathways
    M Phase, Protein targeting to Nucleus
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